Research Overview
My research interests involve (1) the use of multiple imaging methods and computational tools to study information flow in neuronal (brain) networks supporting cognitive information processing, and (2) the research and development of (wearable) Brain-Computer Interface technology. I've led (or contributed to) a range of research projects intersecting the fields of Computational Neuroscience, Machine Learning, Brain-Computer Interfaces, and Human-Computer Interaction (namely, Context-Aware Computing and Ubiquitous Computing).



PUBLICATIONS

* authors contributed equally


PAPERS

Peer-Reviewed:

Makeig, S.*, Kothe, C.*, Mullen, T.*, Bigdely-Shamlo, N., Zhang, Z., Kreutz-Delgado, K (2012). Evolving Signal Processing for Brain-Computer Interface Design. To appear in: IEEE Centennial Celebration Special Issue- Neuroergonomics/BCI. IEEE Transactions in Signal Processing

Makeig, S., Leslie, G., Mullen, T., Sarma, D., Bigdely-Shamlo, N., and Kothe, C (2011) Brain Dynamics of Affective Engagement in a Musical Emotion BCI. Lecture Notes in Computer Science 6975, Springer

Mullen, T., Akalin Acar, Z., Worrell, G., Makeig, S. (2011) Modeling Cortical Source Dynamics and Interactions During Seizure. IEEE Engineering in Biology and Medicine.

Leslie, G.* and Mullen, T.*, (2011) MoodMixer: EEG-based Collaborative Sonification. Proceedings of the International Conference on New Interfaces for Musical Expression. Ed. A.R. Jensenius, A. Tveit, R.I. Godøy, D. Overholt. ISBN: 978-82-991841-7-5

Mullen, T., Warp, R., Jansch, A (2011) Minding the (Transatlantic) Gap: An Internet-Enabled Acoustic Brain-Computer Music Interface. Proceedings of the International Conference on New Interfaces for Musical Expression. Ed. A.R. Jensenius, A. Tveit, R.I. Godøy, Dan Overholt. ISBN: 978-82-991841-7-5.

Delorme, A., Mullen, T., Kothe C., Akalin Acar, Z., Bigdely Shamlo, N., Vankov, A., Makeig, S. (2011) EEGLAB, SIFT, NFT, BCILAB, and ERICA: New tools for advanced EEG/MEG processing. Computational Intelligence and Neuroscience vol. 2011, Article ID 130714, 12 pages.

 

Published Reports (not peer-reviewed):

Mullen, T.R., (2010) The Source Information Flow Toolbox (SIFT): An Electrophysiological Information Flow Toolbox for EEGLAB. Theoretical Handbook and User Manual. Masters Project. www.sccn.ucsd.edu/wiki/SIFT.

Mullen, T., Huang, Q., Reich, J. Towards Ubiquitous Brain-Aware Computing: A Preliminary EEG Study (2007). PARC technical report (pdf)

 

In Review

Bigdely-Shamlo, N., Mullen, T., Kreutz-Delgado, K., Makeig, S., Measure Projection: A Probabilistic Alternative to EEG Independent Component Clustering. NeuroImage

Kang, J.K.*, Mullen, T.*, Makeig, S. Differentiation of EEG patterns with nonconvulsive status epilepticus and triphasic wave using wavelet analysis. Epilepsia


In Final Preparation

Mullen, T., Delorme, A., Makeig, S. The Source Information Flow Toolbox: An Electrophysiological Information Flow Toolbox for EEGLAB. Journal of Neuroscience Methods

Mullen, T.*, Talbott, W.* Probabilistic classification of EEG signals using Symbolic Aggregate Approximation and Latent Dirichlet Allocation. NIPS


ABSTRACTS

2011

Mullen, T., Akalin Acar, Z., Palmer, J., Worrell, G, Makeig, S (2011). Analysis of neuronal source dynamics and connectivity during seizure using adaptive vector autoregressive models, sparse bayesian learning, independent component analysis, and electrocorticography. International Cognitive Science Conference XI, Mallorca, Spain

Thompson, W., Mullen, T., Makeig, S., (2011) A Bayesian spatiotemporal model for multi-subject EEG source dynamics and effective connectivity. International Cognitive Science Conference XI, Mallorca, Spain

2010

Mullen, T., Makeig, S. (2010) An electrophysiological information flow toolbox for EEGLAB. Society for Neuroscience Conference, San Diego, CA

Thompson, W., Ombao H., Mullen, T., Onton., J., Makeig, S. (2010) A bayesian model for EEG frequency-domain functional connectivity. Human Brain Mapping. Barcelona, Spain 

Thompson, WK, Mullen, T., Motta, G., Ombao, H., (2010) Spatiotemporal Factor Analysis of EEG Evolutionary Latent Sources. Human Brain Mapping, Barcelona, Spain.

Mullen, T., Onton, J., Delorme, A., Thompson, W., Makeig, S.  (2010) Analysis and visualization of theta-band information flow dynamics in an ERN-producing task. Human Brain Mapping. Barcelona, Spain and Sloan-Swartz Annual Meeting. New Haven, CT

2009

Mullen T,* Swann N,* Tandon N, Ellmore T, DiSano M, Dreyer S, Aron AR. (2009) Using Granger-causal techniques and intracranial EEG to examine directed information flow in a cortical network for stopping action. Poster. Society for Neuroscience Conference. Chicago, IL.

Velu, P., Hammon, P., Mullen, T., de Sa, V.  (2009) Dissociating visual response and motor preparation for reach prediction from EEG. Poster. Society for Neuroscience Conference. Chicago, IL.

2008

Bastos, A.,* Mullen, T.,* Canolty, R., Pasley, B., Knight, R., Freeman, R. (2008)
SSVEP-based Single-Trial Classification of Attention. Poster. Cognitive Neuroscience Society Conference, San Francisco, CA.

2007

Fuhrmann, G.,* Mullen T.,* Suppiah, S., Soltani, M., Edwards E., Canolty, R., Sarang, D., Kirsch, H., Barbaro, N., Knight, R.T. (2007) Functional Connectivity and Information Flow in the Human Brain during Language Processing: Evidence from ECoG data. Poster. Cognitive Neuroscience Society Conference, New York, N.Y.

2006

Mullen, T., Huang, Q., Reich, J. (2006) Project Halo: Enabling Ubiquitous Brain-Aware Computing. Poster. PARC Annual Poster Session. Palo Alto, CA.

Mullen, T., Bolton, J., Jian, S., Martinez , A. (2006) NEEDster: Need-based Exchange Enhancement Device. Prototype Exhibition, Talk, and Poster. UC Berkeley HCI Poster Session

2005

Padilla, M.L., Mullen T.R., & Knight R.T. (2005) Differential contributions of lateral and orbitofrontal cortex to preparatory attention and action monitoring. Symposium Talk & Poster. Society for Neuroscience Conference, Washington D.C.

 

SYMPOSIA and other invited TALKS

Mullen, T. Lecture series on Advanced EEG Signal Processing (Nov 30 - Dec 2, 2011). Baque Center for Cognition Brain and Language. Donostia/San Sebastian, Basque Autonomous Community, Spain.

Mullen, T., Akalin Acar, Z., Worrell, G., Makeig, S. (2011) Modeling Cortical Source Dynamics and Interactions During Seizure. Oral Presentation. IEEE Engineering in Biology and Medicine. Boston, MA.

Mullen, T.R., Akalin Acar, Z., Palmer, J. (2011) Spatiotemporal Dynamics and Interactions in Intracranial EEG. 2011 Sloan-Swartz Annual Meeting. HHMI Janelia Farm Research Campus. Ashburn, VA, USA.

Mullen, T.R. (2011) Modeling multivariate EEG source information flow using adaptive vector autoregressive models. Symposium Talk. Symposium on EEG advanced signal processing. Aspet, France

Mullen, T.R. (2011) Time-Frequency Analysis, Information Flow, and Granger-Causality. Lecture. Thirteenth International EEGLAB workshop. Aspet, France.

Mullen, T.R. (2011) Analyzing oscillatory EEG/ECoG source dynamics and interactions using the Source Information Flow Toolbox (SIFT). Fourteenth International EEGLAB workshop. ICON XI. Mallorca, Spain.

Mullen, T.R. 
(2010) Modeling Distributed Brain Network Dynamics. Invited Lecture. Twelfth International EEGLAB workshop. UC San Diego, La Jolla, CA, USA (video)


Mullen, T.R. (2010) Information Flow Analysis in EEG. Invited Symposium Talk. Society for Psychophysiological Research. Portland, OR, USA. 

Mullen, T.R. (2010) Modeling effective connectivity by measuring EEG information flow. Invited Lecture. Tenth International EEGLAB workshop. Jyvaskyla, Finland. 




ACKNOWLEDGEMENTS 

(published papers which I've edited or contributed analysis)


Bin, G.; Gao, X.; Wang, Y.; Hong, B.; Gao, S., (2009) VEP-based brain-computer interfaces: time, frequency, and code modulations [Research Frontier]. Computational Intelligence Magazine, IEEE , vol.4, no.4, pp.22-26


Padilla, M., Hale, L., Wood, R., & Knight, R. T. (2006) Lapses in a prefrontal-extrastriate preparatory attention network predict mistakes. Journal of Cognitive Neuroscience.18:1477-1487. (Pubmed Link)


Fuhrmann Alpert, G., Sun, F. T., Handwerker, D., D'Esposito, M., & Knight, R. T. (2007) Information Analysis of Event-Related BOLD Responses. NeuroImage. 34 (4) 1545-1561. (Pubmed Link)



PATENTS

Mullen, T. and Huang, Q. (2007) Brainwave-Facilitated Presenter Feedback Mechanism. USPTO Patent Application 20090143695 (patent pending)


Mullen, T. and Huang, Q. (2007) Brainwave-Aware Sleep Management. United States Patent 7689274



SELECTED TERM RESEARCH PROJECTS

(minimum grade: A)


Mullen, T., Talbott, W. (2008) Probabilistic classification of EEG signals using Symbolic Aggregate Approximation and Latent Dirichlet Allocation. CS250B : Statistical Machine Learning (Prof. Charles Elkan). UC San Diego (pdf)

Mullen, T. (2007) Functional Connectivity and Information Flow in ECoG Data: A Linear Approach. STAT153: Time-Series Analysis (Prof. David Brillinger). UC Berkeley (pdf)

Mullen, T., Bolton, J., Jian, S., Martinez , A. (2006) NEEDster: Need-based Exchange Enhancement Device. Prototype Exhibition, Talk, and Poster. CS160 : User Interface Design (Prof. John Canny). UC Berkeley (jpg)


Mullen, T.  (2006) Dynamic Identification of Focal Cluster ROIs Using Time-lagged Mutual Information. CS182: Neural Basis of Thought and Language (Prof. Srini Narayanan). UC Berkeley (pdf)


Mullen, T.  (2006) ICA-based Identification of Overlapping Spatial Clusters in ECoG Data. VS298: Neural Computation (Prof. Bruno Olshausen). UC Berkeley (pdf)



OTHER

Reviewer for:


Journal of Computational Neuroscience (ad hoc)

Neural Computation (ad hoc)

Journal of Neuroscience (ad hoc)

NeuroImage

Brain Connectivity

IEEE Transactions in Biomedical Engineering


 Copyright (c) 2009 Tim Mullen